expertise

The overarching objective of IBISBA•GR is to build an Industrial Biotechnology RI that offers research expertise for the circular bioeconomy transition. The expertise matches and builds on a much larger range of services already available at IBISBA.EU 

services

Bioprocess Development & Optimisation

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Examples include:

  • Saccharification and fermentation of agro-industrial residues to 2G biofuels (NTUA, CERTH)
  • Production of biopolymer and bioactive compounds using residual biomass and industrial byproducts (NTUA, CERTH)
  • Production of high added value products from lignocellulosic biomass and micro-algae (NTUA, CERTH, NKUA, Ioannina-U)
  • Large-scale production of microorganisms (natural and recombinant) and enzymes with industrial interest (NTUA, NKUA, CERTH)
  • Environmental applications in waste (solid, water, municipal) biotreatment and microbial remediation (Thrace-U, Crete-U, Aegean-U)
  • Enzyme microbial production with industrial interest and pharmaceuticals products, and/or in the desulphurization of petroleum fractions (NTUA, NKUA)

Protein Discovery & Engineering

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Examples include:

  • Retrosynthesis search from chassis to target through efficient and well controlled protocols (NTUA, NHRF, CERTH)
  • Optimization models FBA and THFA to target strain performance
  • Large scale kinetics using ORACLE technology and/or dynamic FBA models (NHRF) to connect strain and process design (NTUA)

Enzyme Technology & Biocatalysis

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Examples include:

  • The development of new biocatalysts, the immobilization of enzymes and multienzymes systems, the immobilization of microorganisms etc. as needed for industrial applications (Ioannina-U, NTUA)
  • Development of innovative biocatalytic reactors (Ioannina-U, NTUA)
  • synthesis/modification of bioactive compounds and biopolymers (NTUA, CERTH)
  • The enzymatic modification of textiles and packaging materials (NTUA)
  • Engineering improved microorganisms to address specs of industrial substrates and processes (CERTH, NKUA, NTUA)

Techno-economic Assessment & Value Chain Analysis

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Examples include:

  • Life Cycle Costing (LCC) and Life Cycle Analysis (LCA) that use cost models (CAPEX and OPEX) to assess capital investment as a function of industrial scale and capacity
  • LCA includes post and ex-ante LCA technology using commercial software (SimaPro, Umberto, CCalC) for mid-point impact, end-point damage, and total score metrics for cradle-to-grave analysis
  • Value chain analysis uses concept-based technology (Total Site Analysis, SCO) to integrate bioprocessing paths and supply chain analysis

Data Management, Data Science, Data Infrastructures

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Examples include:

  • Engineering libraries (NTUA, CERTH) for process synthesis, simulation, process, and energy integration
  • Data applications (ATHENA RC, NTUA, CERTH) that range from digital twins to model embedding (processes), properties and thermodynamics of non-conventional streams, and multi-scale applications

Microbial Strains Development

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National Technical University of Athens School of Chemical Engineering
St. Heroon Polytechniou 9, Zografou Campus, 157 80, Athens, Greece
www.ntua.gr

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